Absolutely!
Just ensure you are using ‘Screen Width’ as the detection method for different layouts, and when you toggle to different views in MarkUp you should see the respective layout for that device type. For more information on marking up Ceros layouts, check out this article!
*NOTE: If someone on your team is commenting on your Ceros experience in MarkUp, be sure to not republish that experience under a new URL until you have addressed all comments on the piece and no longer need to view them. If you change the URL of the experience, MarkUp will not be able to locate existing comments.